Combined Immunodeficiency Disease | Severe

The name comes from David Vetter, a boy with X-linked SCID who lived for 12 years in a sterile NASA-designed plastic bubble. Diagnosis & Symptoms

While T cells are always affected, B cells and Natural Killer (NK) cells may also be missing or non-functional depending on the specific genetic mutation.

Infants often appear because they are temporarily protected by maternal antibodies. Signs usually emerge within the first few months: Severe Combined Immunodeficiency - StatPearls - NCBI - NIH