Anesthetic - Local

Local anesthetics are essential medications that reversibly block pain sensation in specific body parts by inhibiting the conduction of action potentials across nerve fibers. They work by blocking , preventing the influx of sodium ions required for nerve impulse generation. Chemical Classification

: These include commonly used agents like lidocaine , bupivacaine , articaine , mepivacaine , and prilocaine . Amides are metabolized in the liver and are the "gold standard" in modern dentistry due to their safety and lower risk of allergic reactions. local anesthetic

: This class includes procaine (Novocain), tetracaine , and benzocaine . Esters are generally less common today because they are more likely to cause allergic reactions, although procaine is noted for its low toxicity. Pharmacological Considerations Local Anesthetic Toxicity - StatPearls - NCBI Bookshelf Amides are metabolized in the liver and are

Local anesthetics are categorized into two main groups based on their chemical linkage: and prilocaine .