Grey's Anatomy S16e16 -

He apologizes for leaving via a letter and reveals he is filing for divorce. He leaves her his shares in Grey Sloan Memorial Hospital.

He expresses his gratitude for their mentorship over the years. The Big Reveal: Izzie Stevens and the Twins

Season 16, Episode 16 of Grey's Anatomy , titled serves as the official farewell to original cast member Justin Chambers , who played Dr. Alex Karev . The episode aired on March 5, 2020, and is one of the most controversial in the series' history due to how it handles Alex's departure. ✉️ The Core Format: Letters from Alex Grey's Anatomy s16e16

Alex explains she will always be "his person," but he found a reason to stay away that he couldn't ignore.

Izzie has five-year-old twins, Eli and Alexis , who are biologically Alex’s. He apologizes for leaving via a letter and

They make the life-altering decision to foster Joey , a teenager Bailey treated who had been living in the foster care system.

He discovered that Izzie used the embryos they froze years ago when she had cancer. The Big Reveal: Izzie Stevens and the Twins

The central twist of the episode is that Alex has reunited with his ex-wife, .

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