: The effectiveness of the cure is proven immediately when it is administered to Rembrandt's wife, effectively ending that specific plot arc and solidifying Makoto's reputation in the human world. Real-World "Wonder" Drugs
While TSUKIMICHI focuses on magical alchemy, the concept of "wondrous medicine production" mirrors the real-world history of drug development. (Dub) 7 : Wondrous Medicine Production
: For medical professionals of the 1950s and 60s, the development of antibiotics like penicillin was viewed as a "wonder drug" transition from accidental discovery to mass production. : The effectiveness of the cure is proven