Cross-over Review

: Each participant acts as their own "control," which often requires a smaller sample size to achieve statistically significant results.

: Participants are randomized into groups. Group A might receive "Treatment 1" first, followed by a washout period (to clear the first drug from their system), and then "Treatment 2." Group B would receive the treatments in reverse order. Cross-Over

In medicine and clinical research, a is a type of clinical trial where every participant receives multiple treatments in a specific sequence. : Each participant acts as their own "control,"