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: It is "likely effective" for treating thinning vaginal tissue (vaginal atrophy) in postmenopausal women. FDA-approved vaginal inserts are available for this purpose.

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: In women with diminished ovarian reserve, some studies suggest DHEA may improve egg quality, increase pregnancy rates, and lower miscarriage risks when taken under medical supervision for 6–12 weeks before IVF. : It is "likely effective" for treating thinning

: It may improve mood and libido in women with primary or secondary adrenal insufficiency who still feel unwell despite standard hormone replacement. Quality and Purchasing Considerations increase pregnancy rates