There are two primary forms, depending on which protein is missing:
In the 19th and 20th centuries, it was famously known as the "Royal Disease." Queen Victoria was a carrier and passed the gene to various royal houses across Europe, including the ruling families of Spain, Germany, and Russia. The most famous case was Alexei Nikolaevich, the Tsar’s son, whose condition led the family to seek help from the mystic Rasputin, indirectly impacting the Russian Revolution. Types and Severity bleeder's disease
Since males have only one X chromosome (XY), a single faulty gene causes the disease. There are two primary forms, depending on which
