Anorchidism Review

Absence of both testicles. This is rare, occurring in roughly 1 in 20,000 males. Causes and Etiology

This condition is distinct from (undescended testicle), where the testicle is present but not in the scrotum, although they are often clinically confused during initial examination. Types of Anorchidism anorchidism

A common hypothesis is that the testis undergoes twisting (torsion) during fetal development, leading to ischemic necrosis (tissue death) and subsequent absorption of the tissue. Absence of both testicles

Serum Anti-Müllerian Hormone (AMH) levels are crucial markers. Undetectable or very low AMH indicates absence of testicular tissue. Types of Anorchidism A common hypothesis is that

Measuring Hormone levels is critical. Low testosterone and significantly elevated gonadotropins (FSH and LH) in a child with non-palpable testes suggest vanishing testis syndrome.

Anorchidism is generally considered a sporadic, non-genetic disorder, though rare familial occurrences exist.