The study investigates the role of , a protein traditionally known for its function in the ESCRT-III (Endosomal Sorting Complex Required for Transport) pathway, which typically handles late-stage cell division (abscission). The researchers discovered that Chmp4c has a much earlier role:
In scientific publishing, identifiers like "39091" are often used by the journal's hosting platform (in this case, Rockefeller University Press) to link specific multimedia files to their corresponding articles. The video labeled typically displays time-lapse microscopy of: 39091.mp4
: Without proper Chmp4c function, cells often experience errors in chromosome alignment, leading to genomic instability. The study investigates the role of , a
: Visualizing how the spindle forms and interacts with chromosomes in both control cells and Chmp4c-depleted cells to illustrate the paper's findings. : Visualizing how the spindle forms and interacts
The "39091.mp4" file refers to a specific supplemental video associated with a 2018 biology research paper titled , published in the Journal of Cell Biology . Key Findings of the Paper
: Showing the progression of a cell through mitosis.
: It helps regulate the organization and stability of the mitotic spindle , the machinery that pulls chromosomes apart during cell division.