Approximately 9,895 of these ligands have curated quantitative data regarding their interactions with specific biological targets.
The Guide to PHARMACOLOGY is an expert-curated resource that acts as a portal to the properties of drug targets and the prescription medicines that act on them. The identified in the latest database update represent a broad spectrum of chemical and biological substances, including: 13721 rar
The database provides clinical use summaries for 4,257 of these ligands, aiding researchers and medical professionals in understanding their therapeutic applications. Contextual Usage: "RAR" Contextual Usage: "RAR" Out of the total ligand
Out of the total ligand count, 2,196 are officially approved drugs, with 1,238 featuring detailed quantitative interaction data. They are critical in regulating genes responsible for
In a pharmacological context, commonly stands for Retinoic Acid Receptors . These are nuclear receptors that act as transcription factors, mediated by the ligand retinoic acid . They are critical in regulating genes responsible for development, cell differentiation, and cell death. Ligands within the 13,721 count often include synthetic or natural retinoids designed to target these receptors for treating conditions like certain leukemias or skin disorders. Other Potential References